Meet Pi: The Hormone-Sensitive Inflamer 🔥
Anaerobic Inflammatory Pathogen | Orange Complex
Prevotella intermedia — or Pi — is strongly associated with inflammation, swollen tissues, and bleeding gums.
But here’s what makes Pi particularly interesting: its levels may increase during hormonal changes, including pregnancy.
Pi is commonly found in inflamed periodontal tissues and can contribute to continued irritation and inflammation around both teeth and dental implants.
Quick way to remember Pi:
🟠 Orange Complex
🔥 The Hormone-Sensitive Inflamer
🩸 Think bleeding + inflammation
🤰 Levels may increase during hormonal changes and pregnancy
🦷 May contribute to inflammation around teeth and implants
Seeing Pi on a MicrobeLinkDx® Report?
The amount detected, other bacteria present, and the patient’s clinical findings all matter when interpreting the microbial picture.
Pi Research & Updates
We’ll continue adding new research, oral-systemic findings, clinical information, and resources related to Pi as they become available.
